SCHEMBL9757698

SCHEMBL9757698

CCC/C=C(\C)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
TBXAS1 P24557 2/20 0.41
KDM1A O60341 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
ATM Q13315 1/20 0.39
LMNA P02545 1/20 0.38
PTGS2 P35354 1/20 0.38
CYP2D6 P10635 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10907609 1.00 CYP1A2 (0.42) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
SCHEMBL1193728 1.00 CYP1A2 (0.42) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
SCHEMBL11023529 0.89 ESR1 (0.37) CYP3A4TBXAS1CYP2D6
SCHEMBL30705332 0.89 KDM1A (0.44) CYP1A2TBXAS1KDM1ACES2CES1
SCHEMBL1053053 0.88 TBXAS1 (0.45) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
SCHEMBL1053054 0.88 TBXAS1 (0.45) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
SCHEMBL21462939 0.88 TBXAS1 (0.45) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
Styrene SCHEMBL10437141 0.88 ALDH1A1 (0.47) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
Styrene SCHEMBL10437143 0.88 ALDH1A1 (0.47) CYP1A2ALDH1A1CYP3A4TSHRTBXAS1
SCHEMBL2768533 0.86 TBXAS1 (0.48) TBXAS1CES2CES1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903581-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I BASF SE (DE) 2021-11-03 EP disclosed
CN-110903172-B Method for stereoselectively synthesizing (E) -tri-substituted olefin 温州大学 2021-08-24 CN disclosed
CN-110903172-A Method for stereoselectively synthesizing (E) -tri-substituted olefin 温州大学 2020-03-24 CN disclosed
US-5049685-A Nuclear substituted salicylic acids and their salts SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1991-09-17 US disclosed