Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564649 | 0.82 | MAOB (0.45) | PTGDR2S1PR5MAOBSMN1; SMN2HRH3 | |
| SCHEMBL5380988 | 0.74 | MMP13 (0.49) | PTGDR2SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL5381126 | 0.73 | PTGDR2 (0.48) | PTGDR2S1PR5MAOBHRH3NR4A2 | |
| SCHEMBL7549149 | 0.72 | GPR34 (0.43) | PTGDR2S1PR5MAOBSMN1; SMN2KCNK3 | |
| SCHEMBL5381994 | 0.72 | KMT2A (0.44) | S1PR5MAOBSMN1; SMN2HRH3NR4A2 | |
| SCHEMBL5383039 | 0.71 | GAA (0.68) | MAOBSMN1; SMN2HRH3MEN1LMNA | |
| SCHEMBL5383037 | 0.71 | GAA (0.68) | MAOBSMN1; SMN2HRH3MEN1LMNA | |
| SCHEMBL2367511 | 0.71 | MEN1 (0.60) | PTGDR2SMN1; SMN2PRKAA2MEN1LMNA | |
| SCHEMBL5381942 | 0.71 | SMN1; SMN2 (0.58) | PTGDR2MAOBSMN1; SMN2MEN1LMNA | |
| SCHEMBL5372015 | 0.71 | KMT2A (0.65) | SMN1; SMN2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |