Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 6/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549244 | 0.87 | PANK3 (0.50) | PANK3HTR2CTLR7ACHEEIF4E | |
| SCHEMBL3538271 | 0.83 | HTR2C (0.64) | PANK3HTR2CTLR7ACHEEIF4E | |
| SCHEMBL13548732 | 0.77 | HTR2C (0.62) | PANK3HTR2CTLR7ACHEEIF4E | |
| SCHEMBL7549240 | 0.77 | PANK3 (0.71) | PANK3HTR2CTLR7ALDH1A1KDM4E | |
| SCHEMBL13548679 | 0.74 | HTR2C (0.62) | PANK3HTR2CTLR7ACHEEIF4E | |
| SCHEMBL3539520 | 0.73 | HTR2C (0.64) | PANK3HTR2CTLR7ACHEEIF4E | |
| Acetic Acid SCHEMBL31255965 | 0.73 | ACHE (0.52) | PANK3HTR2CTLR7ACHEALDH1A1 | |
| SCHEMBL25410319 | 0.73 | KDM4E (0.55) | HTR2CTLR7ACHEALDH1A1KDM4E | |
| SCHEMBL2691637 | 0.73 | ACHE (0.61) | HTR2CTLR7ACHEEIF4EALDH1A1 | |
| SCHEMBL3535303 | 0.71 | PANK3 (0.57) | PANK3HTR2CTLR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237849-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2002-09-11 | — | — | EP | claimed |
| WO-2001032604-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2001-05-10 | — | — | WO | claimed |