SCHEMBL754927

SCHEMBL754927

CCCC(Sc1nc2ccccc2[nH]1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.65
KMT2A Q03164 4/20 0.63
POLB P06746 6/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TXN P10599 1/20 0.49
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10872581 0.89 POLB (0.70) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL8973070 0.87 KMT2A (0.63) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL757400 0.85 KMT2A (0.67) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL9305881 0.85 KMT2A (0.61) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL10759269 0.84 KMT2A (0.60) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL3262828 0.82 SMN1; SMN2 (0.49) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL9305912 0.81 SMN1; SMN2 (0.61) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL10645047 0.81 SMN1; SMN2 (0.61) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL10641582 0.81 SMN1; SMN2 (0.61) SMN1; SMN2KMT2APOLBALDH1A1LMNA
SCHEMBL10643667 0.81 SMN1; SMN2 (0.57) SMN1; SMN2KMT2APOLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
US-20060229407-A1 Light stabilising polymer dispersants in pigment dispersions CIBA SPECIALTY CHEMICALS CORP. 2006-10-12 US disclosed