O-Xylene

O-Xylene

SCHEMBL7549304

Cc1ccc2c(C)cccc2c1.Cc1ccccc1C

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 0.91
CYP2A6 P11509 7/20 0.63
ALDH1A1 P00352 5/20 0.60
TDP1 Q9NUW8 2/20 0.54
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 2/20 0.43
ACHE P22303 2/20 0.43
CYP3A4 P08684 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KIF11 P52732 1/20 0.39
NQO2 P16083 1/20 0.39
MAOA P21397 2/20 0.39
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29453431 0.96 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL29580405 0.96 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL599599 0.96 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1TDP1HPGD
Ammonia Solution, Strong SCHEMBL27937838 0.93 CYP1A2 (0.95) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL588278 0.88 CYP1A2 (0.84) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL31484861 0.84 CYP1A2 (0.78) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL28828757 0.84 CYP1A2 (0.78) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL9614972 0.84 CYP1A2 (0.70) CYP1A2CYP2A6ALDH1A1TDP1HPGD
SCHEMBL5494664 0.83 CYP2A6 (0.70) CYP1A2CYP2A6ALDH1A1TDP1HPGD
O-Xylene SCHEMBL7555306 0.83 CYP2A6 (0.91) CYP1A2CYP2A6ALDH1A1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996608-B1 METHOD OF MAKING 2,6-DIMETHYLNAPHTHALENE FROM OTHER DIMETHYLNAPHTHALENE ISOMERS AND FROM DIMETHYLTETRALINS/DIMETHYLDECALINS WITH A METHYL GROUP ON EACH RING CHEVRON PHILLIPS CHEMICAL CO (US) 2002-07-03 EP disclosed