O-Xylene

O-Xylene

SCHEMBL7555306

Cc1ccc2cccc(C)c2c1.Cc1ccccc1C

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 9/20 0.91
CYP1A2 P05177 8/20 0.91
ALDH1A1 P00352 4/20 0.62
HSD17B10 Q99714 3/20 0.62
HPGD P15428 2/20 0.62
TDP1 Q9NUW8 4/20 0.54
MAOA P21397 1/20 0.46
TSHR P16473 4/20 0.45
ACHE P22303 2/20 0.43
CYP3A4 P08684 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
THRB P10828 1/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
NOX1 Q9Y5S8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470563 0.96 CYP1A2 (1.00) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL597735 0.96 CYP1A2 (1.00) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL27919256 0.93 CYP1A2 (0.95) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL6550685 0.89 CYP2A6 (0.88) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL588278 0.88 CYP1A2 (0.84) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL9011194 0.87 CYP1A2 (0.75) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL28887801 0.84 CYP1A2 (0.78) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL5494664 0.83 CYP2A6 (0.70) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL10320994 0.83 CYP1A2 (0.75) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD
O-Xylene SCHEMBL7549304 0.83 CYP1A2 (0.91) CYP2A6CYP1A2ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996608-B1 METHOD OF MAKING 2,6-DIMETHYLNAPHTHALENE FROM OTHER DIMETHYLNAPHTHALENE ISOMERS AND FROM DIMETHYLTETRALINS/DIMETHYLDECALINS WITH A METHYL GROUP ON EACH RING CHEVRON PHILLIPS CHEMICAL CO (US) 2002-07-03 EP disclosed
US-6015930-A HYDROISOMERIZING WITH ACIDIC CATALYST AND METAL, DEHYDROGENATING WITH REFORMING CATALYST CHEVRON CHEMICAL COMPANY (US) 2000-01-18 US disclosed