SCHEMBL9614972

SCHEMBL9614972

Cc1ccc2c(C)cccc2c1.Cc1ccc2ccccc2c1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 9/20 0.70
CYP2A6 P11509 7/20 0.63
TSHR P16473 3/20 0.63
ALDH1A1 P00352 6/20 0.57
HSD17B10 Q99714 5/20 0.54
HPGD P15428 4/20 0.54
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAOA P21397 2/20 0.45
CYP3A4 P08684 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HIF1A Q16665 2/20 0.41
MAPK1 P28482 1/20 0.41
CASP1 P29466 1/20 0.41
RAB9A P51151 1/20 0.41
CASP7 P55210 1/20 0.41
ATM Q13315 1/20 0.41
CYP1B1 Q16678 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011194 0.90 CYP1A2 (0.75) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL16041206 0.88 CYP1A2 (0.83) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL15224424 0.87 CYP1A2 (0.59) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL16042477 0.86 CYP2A6 (0.73) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL588278 0.84 CYP1A2 (0.84) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL5494664 0.84 CYP2A6 (0.70) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
O-Xylene SCHEMBL7549304 0.84 CYP1A2 (0.91) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL9010933 0.84 CYP1A2 (0.83) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL29453431 0.84 CYP1A2 (1.00) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL599166 0.84 ALDH1A1 (0.63) CYP1A2CYP2A6TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511207-A1 A PROCESS FOR THE CATALYTIC DISPROPORTIONATION OF METHYLNAPHTHALENES. MOBIL OIL CORP (US) 1992-11-04 EP disclosed
EP-0511207-A4 A PROCESS FOR THE CATALYTIC DISPROPORTIONATION OF METHYLNAPHTHALENES. MOBIL OIL CORP (US) 1992-09-03 EP disclosed