Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674510 | 0.94 | EDNRA (0.47) | EDNRAEDNRB | |
| SCHEMBL31598837 | 0.94 | EDNRA (0.47) | EDNRAEDNRB | |
| SCHEMBL27342900 | 0.79 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL8474145 | 0.77 | BRD4 (0.49) | EDNRAEDNRB | |
| SCHEMBL8479007 | 0.77 | EDNRB (0.46) | EDNRAEDNRB | |
| SCHEMBL7850630 | 0.77 | CA2 (0.44) | EDNRAEDNRB | |
| SCHEMBL7549323 | 0.76 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL8479976 | 0.75 | BRD4 (0.47) | EDNRAEDNRB | |
| SCHEMBL8474214 | 0.75 | BRD4 (0.47) | EDNRAEDNRB | |
| SCHEMBL8347239 | 0.75 | CA2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094816-A4 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2001-12-19 | — | — | EP | claimed |
| EP-1094816-A1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-05-02 | — | — | EP | claimed |
| WO-2000001389-A1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB CO. (US) | 2000-01-13 | — | — | WO | claimed |
| EP-1237888-A2 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044239-A2 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB CO. (US) | 2001-06-21 | — | — | WO | disclosed |