SCHEMBL7549374

SCHEMBL7549374

C=Cc1ccccc1-c1ccccc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
MAPK1 P28482 2/20 0.44
HSD11B1 P28845 3/20 0.36
LMNA P02545 2/20 0.34
PBRM1 Q86U86 1/20 0.34
IDO1 P14902 1/20 0.34
CNR1 P21554 1/20 0.34
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MPI P34949 1/20 0.33
DCUN1D1 Q96GG9 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALPI P09923 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132630 0.85 ALDH1A1 (0.55) ALDH1A1MAPK1LMNAMAPTKDM4E
SCHEMBL7107668 0.83 ALDH1A1 (0.52) ALDH1A1MAPK1LMNAMAPTKDM4E
SCHEMBL28281823 0.83 ALDH1A1 (0.52) ALDH1A1MAPK1LMNAMAPTKDM4E
SCHEMBL50072 0.80
SCHEMBL29418131 0.80
Phosphine SCHEMBL8973573 0.78 ALDH1A1 (0.48) ALDH1A1MAPK1HSD11B1LMNAMAPT
SCHEMBL1984908 0.77 LMNA (0.52) ALDH1A1MAPK1HSD11B1LMNAGAA
SCHEMBL31588291 0.77 LMNA (0.52) ALDH1A1MAPK1HSD11B1LMNAGAA
SCHEMBL358976 0.77 ALDH1A1 (0.67) ALDH1A1MAPK1HSD11B1LMNAPBRM1
SCHEMBL31295703 0.77 ALDH1A1 (0.67) ALDH1A1MAPK1HSD11B1LMNAPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US claimed
EP-1211284-A1 Semi-finished products or moulded materials of improved toughness made from propylene polymers Borealis GmbH (AT) 2002-06-05 EP disclosed
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US disclosed
EP-0884356-A2 Blends of polyolefins and syndiotactic vinyl polymeres PCD Polymere AG (AT) 1998-12-16 EP disclosed
CN-1137788-A Process for making polyphenols from ketones or aldehydes and phenols DOW CHEMICAL CO (US) 1996-12-11 CN disclosed