Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549410 | 1.00 | CES1 (0.43) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL19004689 | 0.83 | CES1 (0.36) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL21791732 | 0.81 | CES1 (0.41) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL22432863 | 0.80 | CES1 (0.38) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL10791805 | 0.79 | CYP3A4 (0.52) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL20622297 | 0.78 | CES1 (0.43) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL1245527 | 0.78 | CES1 (0.48) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL1245523 | 0.78 | CES1 (0.48) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL18620042 | 0.77 | HTR3E (0.50) | CYP3A4ALDH1A1MEN1KMT2AHDAC8 | |
| SCHEMBL88389 | 0.76 | CES1 (0.40) | CES1CES2AKR1B1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620219-B1 | Process for producing sulfolane compounds | PHILLIPS PETROLEUM CO (US) | 1998-11-11 | — | — | EP | claimed |
| EP-0620219-A1 | Process for producing sulfolane compounds | PHILLIPS PETROLEUM COMPANY (US) | 1994-10-19 | — | — | EP | claimed |
| US-5347018-A | Freezing point depressants | PHILLIPS PETROLEUM COMPANY (US) | 1994-09-13 | — | — | US | claimed |
| US-5290953-A | Sulfurization of conjugated diene; catalytic hydrogenation | PHILLIPS PETROLEUM COMPANY (US) | 1994-03-01 | — | — | US | claimed |
| EP-1123286-A4 | SULFOLANE AND PROCESS THEREFOR | PHILLIPS PETROLEUM CO (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1123286-A1 | SULFOLANE AND PROCESS THEREFOR | Phillips Petroleum Company (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000017189-A1 | SULFOLANE AND PROCESS THEREFOR | PHILLIPS PETROLEUM COMPANY (US) | 2000-03-30 | — | — | WO | disclosed |
| US-6034254-A | REACTIG CONJUGATED DIENE WITH SULFUR DIOXIDE; HYDROGENATION | PHILLIPS PETROLEUM COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0620219-B1 | Process for producing sulfolane compounds | PHILLIPS PETROLEUM CO (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5512261-A | CIRCULATING LOOP; SPRAYING | PHILLIPS PETROLEUM COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0620219-A1 | Process for producing sulfolane compounds | PHILLIPS PETROLEUM COMPANY (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5347018-A | Freezing point depressants | PHILLIPS PETROLEUM COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5290953-A | Sulfurization of conjugated diene; catalytic hydrogenation | PHILLIPS PETROLEUM COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| US-4256903-A | REACTING SULFUR DIOXIDE AND CONJUGATED DIENES IN THE PRESENCE OF A MONO OR DI-ALKENYL AMINE | PHILLIPS PETROLEUM COMPANY (US) | 1981-03-17 | — | — | US | disclosed |