SCHEMBL88389

SCHEMBL88389

C=CC(=CCOCC=C(C=C)Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.40
CES2 O00748 1/20 0.38
AKR1B1 P15121 1/20 0.38
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
PAM P19021 1/20 0.34
BTN3A1 O00481 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7549410 0.76 CES1 (0.43) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL7549409 0.76 CES1 (0.43) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL21791732 0.75 CES1 (0.41) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL10791805 0.73 CYP3A4 (0.52) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL60174 0.69 AKT1 (0.42) CES1ALDH1A1MAPK1DRD2HTR2A
SCHEMBL21549608 0.69 CALM1 (0.43) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL19004689 0.69 CES1 (0.36) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL8550603 0.69 CES1 (0.48) CES1CES2AKR1B1TSHRALDH1A1
SCHEMBL1073587 0.67 CES1 (0.46) CES1CES2AKR1B1TSHRALDH1A1
Benzene SCHEMBL28149238 0.67 CES1 (0.46) CES1CES2AKR1B1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129074-B2 Crosslinked nano-inorganic particle/polymer electrolyte membrane for membrane electrode assembly JAPAN ATOMIC ENERGY AGENCY (JP) 2012-03-06 US disclosed
US-20070207359-A1 Crosslinked nano-inorganic particle/polymer electrolyte membrane and method for producing same, and membrane electrode assembly using same JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-06 US disclosed