Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652310 | 0.76 | RET (0.41) | RETMAPK14CAMK1DHDAC6 | |
| SCHEMBL7549758 | 0.74 | RET (0.35) | RETMAPK14CAMK1D | |
| SCHEMBL7546802 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL30226116 | 0.72 | RET (0.48) | RETMAPK14CAMK1DTBXA2RHDAC6 | |
| SCHEMBL23359376 | 0.72 | RET (0.48) | RETMAPK14CAMK1DTBXA2RHDAC6 | |
| SCHEMBL23359386 | 0.72 | RET (0.48) | RETMAPK14CAMK1DTBXA2RHDAC6 | |
| SCHEMBL23359371 | 0.72 | RET (0.48) | RETMAPK14CAMK1DTBXA2RHDAC6 | |
| SCHEMBL7553103 | 0.71 | RET (0.35) | RETMAPK14CAMK1DHDAC6 | |
| SCHEMBL19742869 | 0.69 | RET (0.35) | RETMAPK14CAMK1DHDAC6 | |
| SCHEMBL15973471 | 0.69 | RET (0.35) | RETMAPK14CAMK1DHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746552-B1 | TETRAHYDROFURANS AND TETRAHYDROPYRANS | GIVAUDAN SA (CH) | 2002-06-12 | — | — | EP | disclosed |
| US-5665696-A | ODORANT COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1997-09-09 | — | — | US | disclosed |
| EP-0746552-A1 | TETRAHYDROFURANS AND TETRAHYDROPYRANS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1996-12-11 | — | — | EP | disclosed |
| WO-1996020185-A2 | TETRAHYDROFURANS AND TETRAHYDROPYRANS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1996-07-04 | — | — | WO | disclosed |