SCHEMBL19742869

SCHEMBL19742869

CC1(C)C2CCC(C=O)C1C2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.35
MAPK14 Q16539 1/20 0.35
CAMK1D Q8IU85 1/20 0.35
HDAC6 Q9UBN7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15973471 1.00 RET (0.35) RETMAPK14CAMK1DHDAC6
SCHEMBL19742870 1.00 RET (0.35) RETMAPK14CAMK1DHDAC6
SCHEMBL19742871 1.00 RET (0.35) RETMAPK14CAMK1DHDAC6
SCHEMBL30832584 1.00 RET (0.35) RETMAPK14CAMK1DHDAC6
SCHEMBL9184208 0.77 TDP1 (0.36)
SCHEMBL9187247 0.77 TDP1 (0.36)
SCHEMBL2852181 0.77 TDP1 (0.36)
SCHEMBL12586057 0.75
SCHEMBL12586047 0.75
SCHEMBL283840 0.73 CDK5 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709160-A1 STABLE OIL-IN-WATER MICROEMULSION COMPOSITIONS S.C. Johnson & Son, Inc. (US) 2026-03-18 EP disclosed
US-20250290009-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2025-09-18 US disclosed
CN-119790032-A Dimethyl bicycloheptenyl and dimethyl bicycloheptyl derivatives and their use as flavouring agents 奇华顿股份有限公司 2025-04-08 CN disclosed
EP-4522714-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING Firmenich SA (CH) 2025-03-19 EP disclosed
US-20240373861-A1 STABLE OIL-IN-WATER MICROEMULSION COMPOSITIONS S. C. JOHNSON & SON, INC. 2024-11-14 US disclosed
WO-2024233869-A1 STABLE OIL-IN-WATER MICROEMULSION COMPOSITIONS S. C. JOHNSON & SON, INC. (US) 2024-11-14 WO disclosed
CN-118894782-A Sun-screening compound, cosmetic and preparation method 湖州闪思新材料科技有限公司 2024-11-05 CN disclosed
CN-117337138-A Controlled release delivery compositions for extending shelf life of perishable goods and methods of making and using the same RYP实验室有限公司 2024-01-02 CN disclosed
WO-2023217712-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2023-11-16 WO disclosed
CN-113301802-B Synergistic preservative compositions, methods of making and methods of use thereof ISP投资有限公司 2023-08-25 CN disclosed
CN-116539768-A Analysis method of volatile organic compounds in hops or hops essential oil and application thereof 广州南沙珠江啤酒有限公司 2023-08-04 CN disclosed
CN-115701912-A Sweetening compositions and uses thereof 弗门尼舍有限公司 2023-02-14 CN disclosed
CN-111533648-B Preparation method of lyral 南平青华科技有限公司 2023-02-14 CN disclosed
US-11566265-B2 Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-01-31 US disclosed
CN-114804996-A Method for synthesizing beta-myrcene through intramolecular decarboxylation allyl substitution reaction 万华化学集团股份有限公司 2022-07-29 CN disclosed
CN-114525174-A Green tangerine fragrance compound and green tangerine type essence 东莞波顿香料有限公司 2022-05-24 CN disclosed
CN-114390926-A Sake replica prepared from individual components 艾娃食品实验室股份有限公司 2022-04-22 CN disclosed
US-10421727-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2019-09-24 US disclosed
US-20170369447-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421727-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM7, TRPA1 RET 3006/4885MAPK14 1703/4885CAMK1D 376/4885
US-20170369447-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM7, TRPA1 RET 3006/4885MAPK14 1703/4885CAMK1D 376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.