Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38675 | 1.00 | TTR (0.44) | TTRALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL11656743 | 0.98 | TTR (0.43) | TTRALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL757243 | 0.94 | TTR (0.41) | TTRALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL29413345 | 0.90 | TRPA1 (0.44) | TTRLMNANFE2L2MAPT | |
| SCHEMBL6050457 | 0.90 | TTR (0.49) | TTRTDP1DAPK1AURKAAURKB | |
| SCHEMBL722164 | 0.90 | TRPA1 (0.44) | TTRLMNANFE2L2MAPT | |
| SCHEMBL29521321 | 0.90 | TTR (0.49) | TTRTDP1DAPK1AURKAAURKB | |
| SCHEMBL6050449 | 0.90 | TTR (0.49) | TTRTDP1DAPK1AURKAAURKB | |
| SCHEMBL8076468 | 0.88 | TRPA1 (0.43) | TTRLMNANFE2L2MAPT | |
| SCHEMBL11537919 | 0.88 | TTR (0.47) | TTRALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444091-B1 | MIXING PULPS WITH POLYAMIDES OR IN COMBINATION WITH COAGULANTS, FLOCCULANTS AND/OR PARTICLES; EFFICIENCY | NALCO CHEMICAL COMPANY | 2002-09-03 | — | — | US | disclosed |
| WO-2002052102-A2 | STRUCTURALLY RIGID NONIONIC AND ANIONIC POLYMERS AS RETENTION AND DRAINAGE AIDS IN PAPERMAKING | ONDEO NALCO COMPANY (US) | 2002-07-04 | — | — | WO | disclosed |