SCHEMBL722164

SCHEMBL722164

Nc1cccc(C=Cc2ccccc2)c1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
MAPT P10636 1/20 0.41
NFE2L2 Q16236 5/20 0.41
CYP19A1 P11511 2/20 0.41
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
DHFR P00374 1/20 0.40
TTR P02766 1/20 0.38
CHAT P28329 1/20 0.37
GRM4 Q14833 1/20 0.37
LMNA P02545 1/20 0.37
PPARG P37231 1/20 0.37
NR1H2 P55055 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413345 1.00 TRPA1 (0.44) TRPA1MAPTNFE2L2CYP19A1MAOA
SCHEMBL8076471 0.98 TRPA1 (0.43) TRPA1MAPTNFE2L2CYP19A1MAOA
SCHEMBL8076468 0.98 TRPA1 (0.43) TRPA1MAPTNFE2L2CYP19A1MAOA
SCHEMBL28965317 0.90 DHFR (0.37) TRPA1MAPTNFE2L2CYP19A1MAOA
SCHEMBL38675 0.90 TTR (0.44) MAPTNFE2L2TTRLMNA
SCHEMBL7549672 0.90 TTR (0.44) MAPTNFE2L2TTRLMNA
SCHEMBL757243 0.88 TTR (0.41) MAPTNFE2L2MAOATTR
SCHEMBL11656743 0.88 TTR (0.43) NFE2L2TTRLMNA
SCHEMBL1719173 0.87 TRPA1 (0.41) TRPA1MAPTNFE2L2CYP19A1MAOA
1,2,4-Triazole SCHEMBL9403269 0.85 DHFR (0.34) TRPA1MAPTNFE2L2CYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117623991-A Polysubstituted aryl cyclopropylamine urea compound, preparation method and application thereof 上海爱博医药科技有限公司 2024-03-01 CN claimed
CN-113480911-B Preparation method and equipment of primer 天途路业集团有限公司 2022-06-21 CN claimed
EP-2310319-A2 GYPSUM-FIBRE COMPOSITE PRODUCT AND PAPER COMPRISING SUCH Kemira OYJ (FI) 2011-04-20 EP claimed
WO-2010018301-A2 GYPSUM PRODUCT KEMIRA OYJ (FI) 2010-02-18 WO claimed
EP-2118012-A2 GYPSUM PRODUCT AND PROCESS FOR ITS PREPARATION Kemira OYJ (FI) 2009-11-18 EP claimed
EP-2118013-A2 A PROCESS FOR PRODUCING GYPSUM Kemira OYJ (FI) 2009-11-18 EP claimed
WO-2008092990-A2 GYPSUM PRODUCT AND PROCESS FOR ITS PREPARATION KEMIRA OYJ (FI) 2008-08-07 WO claimed
WO-2008092991-A2 A PROCESS FOR PRODUCING GYPSUM KEMIRA OYJ (FI) 2008-08-07 WO claimed
EP-0922699-B1 Asymmetric stilbene compounds useful as sun protection agents CIBA SC HOLDING AG (CH) 2004-11-17 EP claimed
CN-1130352-C Asymmetric stilbene compounds CIBA SC HOLDING AG (CH) 2003-12-10 CN claimed
EP-1254900-A2 Triazine derivatives as fluorescent whitening agents, as UV absorbers and their use to increase the sun protection factor of textile materials Ciba SC Holding AG (CH) 2002-11-06 EP claimed
US-6143889-A Asymmetric stilbene compounds CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-07 US claimed
US-5939379-A ULTRAVIOLET ABSORBING AGENT; FLUORESCENT WHITENING AGENT CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-17 US claimed
CN-1224006-A Asymmetric stilbene compounds CIBA SC HOLDING AG (CH) 1999-07-28 CN claimed
EP-0922699-A1 Asymmetric stilbene compounds useful as sun protection agents Ciba SC Holding AG (CH) 1999-06-16 EP claimed
US-5892031-A FLUORESCENT WHITENING AGENTS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US claimed
EP-0825188-A1 Triazine derivatives as fluorescent whitening agents, as UV absorbers and their use to increase the sun protection factor of textile material Ciba SC Holding AG (CH) 1998-02-25 EP claimed
EP-0808837-A1 Stilbene compounds as fluorescent whitening agents, as UV absorbers and their use to increase the sun protection factor of textile material Ciba SC Holding AG (CH) 1997-11-26 EP claimed
EP-0728749-A2 Triazine derivatives, their preparation and use CIBA-GEIGY AG (CH) 1996-08-28 EP claimed
US-4791211-A Process for the production of 2-stilbylnaphthotriazole optical bleaches CIBA-GEIGY CORPORATION (US) 1988-12-13 US claimed