Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29127872 | 0.96 | CALM1 (0.60) | CALM1TAAR1AOC3IGF1RALOX15 | |
| Iodide SCHEMBL7544118 | 0.87 | TAAR1 (0.59) | CALM1TAAR1AOC3TUBB4ATUBB | |
| SCHEMBL244070 | 0.84 | CALM1 (0.79) | CALM1TAAR1AOC3IGF1RALOX15 | |
| SCHEMBL4254058 | 0.84 | CALM1 (0.72) | CALM1TAAR1AOC3IGF1RALOX15 | |
| SCHEMBL10571532 | 0.82 | CALM1 (0.69) | CALM1TAAR1AOC3IGF1RALOX15 | |
| SCHEMBL17400406 | 0.82 | CALM1 (0.69) | CALM1TAAR1AOC3IGF1RALOX15 | |
| SCHEMBL11007798 | 0.82 | CALM1 (0.69) | CALM1TAAR1AOC3IGF1RALOX15 | |
| SCHEMBL9509173 | 0.82 | CALM1 (0.69) | CALM1TAAR1AOC3IGF1RALOX15 | |
| SCHEMBL834551 | 0.79 | TAAR1 (0.73) | CALM1TAAR1AOC3TUBB4ATUBB | |
| SCHEMBL31344104 | 0.79 | CALM1 (0.60) | CALM1TAAR1AOC3IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482990-B1 | Prostaglandin E analogues | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1211241-A1 | PROSTAGLANDIN E ANALOGUES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-06-05 | — | — | EP | disclosed |