Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.79 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.67 |
| ▸ | IGF1R | P08069 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254058 | 0.95 | CALM1 (0.72) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL11007798 | 0.92 | CALM1 (0.69) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL17400406 | 0.92 | CALM1 (0.69) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL10571532 | 0.92 | CALM1 (0.69) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL9509173 | 0.92 | CALM1 (0.69) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL5632470 | 0.91 | LTA4H (0.69) | CALM1TAAR1IGF1RALOX15ALOX5 | |
| SCHEMBL834551 | 0.89 | TAAR1 (0.73) | CALM1TAAR1MAOBIDO1CA12 | |
| SCHEMBL10569081 | 0.88 | MAOB (0.70) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL145506 | 0.88 | CALM1 (0.64) | CALM1TAAR1IGF1RALOX15MAOB | |
| SCHEMBL6568496 | 0.87 | CALM1 (0.63) | CALM1TAAR1IGF1RALOX15MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246931-A1 | PROCESS FOR THE PREPARATION OF TAZOBACTAM | HOSPIRA, INC. (US) | 2015-09-03 | — | — | US | claimed |
| EP-2892903-A1 | PROCESS FOR THE PREPARATION OF TAZOBACTAM | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037893-A1 | PROCESS FOR THE PREPARATION OF TAZOBACTAM | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2014-03-13 | — | — | WO | claimed |
| CN-102356121-A | Uv and light protective film | HUHTAMAKI FORCHHEIM | 2012-02-15 | — | — | CN | claimed |
| EP-1594505-A4 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-08-13 | — | — | EP | claimed |
| US-7122559-B2 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-17 | — | — | US | claimed |
| EP-1594505-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-11-16 | — | — | EP | claimed |
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | claimed |
| WO-2004072101-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-26 | — | — | WO | claimed |
| US-6271383-B1 | USEFUL ACTIVITY AGAINST GRAM-POSITIVE PATHOGENS; IN PARTICULAR, AGAINST VARIOUS STRAINS EXHIBITING RESISTANCE TO VANCOMYCIN AND AGAINST E. FAECIUM STRAINS RESISTANT TO BOTH AMINOGLYCOSIDES AND CLINICALLY USED BETA-LACTAMS. | ZENECA LIMITED (GB) | 2001-08-07 | — | — | US | claimed |
| US-5149802-A | Chemical intermediates for antibiotics | MERCIAN CORPORATION (JP) | 1992-09-22 | — | — | US | claimed |
| US-5075435-A | Chemical intermediates for 1-methylcarbapenicillin | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-12-24 | — | — | US | claimed |
| US-5053500-A | INTERMEDIATES FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | claimed |
| US-4925934-A | DEESTERIFICATION | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-05-15 | — | — | US | claimed |
| EP-0331146-A1 | Process for preparation of beta-lactam derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | claimed |
| WO-1988001619-A1 | 1'-METHYL-BETA-LACTAM COMPOUNDS AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-03-10 | — | — | WO | claimed |
| US-4650868-A | 7-deazapurine derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-17 | — | — | US | claimed |
| US-4556514-A | INTERMEDIATES FOR PRODUCTION OF CARBAPENEM OR PENEM DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-12-03 | — | — | US | claimed |
| EP-0106652-A1 | Beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-04-25 | — | — | EP | claimed |
| EP-0023097-A1 | De-arylmethylation of N-mono- or N-diarylmethyl-beta-lactams; novel azetizinones having anti-bacterial activity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204412-A1 | Phenylglycine derivatives useful as serine protease inhibitors | F7, SERPINE1, HABP2 | CALM1 4737/4885TAAR1 2915/4885IGF1R 1309/4885 |
| US-20150246931-A1 | PROCESS FOR THE PREPARATION OF TAZOBACTAM | FDPS, BPGM, MPST | CALM1 2237/4885TAAR1 3724/4885IGF1R 4077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.