Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120398 | 0.92 | SIRT1 (0.46) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7116460 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7551438 | 0.82 | SIRT1 (0.38) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7115559 | 0.82 | KDM4E (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7121362 | 0.80 | SIRT1 (0.55) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7117408 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7114815 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7120420 | 0.71 | HSD17B10 (0.74) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7121392 | 0.70 | KDM4E (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL17505210 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244629-A2 | QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001046150-A2 | QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |