SCHEMBL7549880

SCHEMBL7549880

C=C(C(=O)O)C(C=C(C)C(=O)O)CCCCCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
GPR84 Q9NQS5 7/20 0.41
FFAR1 O14842 2/20 0.41
MAPT P10636 1/20 0.40
FFAR4 Q5NUL3 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.37
EP300 Q09472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787511 0.93 ACHE (0.37) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL8506548 0.92 LCK (0.37) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL4477399 0.84 LCK (0.36) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL4477552 0.84 LCK (0.36) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL4442361 0.81 FFAR1 (0.42) PPARDGPR84FFAR1MAPTFFAR4
SCHEMBL8673348 0.81 CA2 (0.33)
SCHEMBL8187288 0.81 ACHE (0.31)
SCHEMBL693962 0.80
SCHEMBL6550562 0.79
SCHEMBL9635881 0.79 TSHR (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343840-B2 Particulate polymers, their production and uses CIBA SPEC CHEM WATER TREAT LTD (GB) 2002-07-10 EP disclosed
EP-0343840-B1 Particulate polymers, their production and uses ALLIED COLLOIDS LTD (GB) 1996-12-18 EP disclosed
US-4950725-A THICKENERS USED AS TEXTILE PIGMENT PRINT PASTE ALLIED COLLOIDS LIMITED (GB) 1990-08-21 US disclosed
EP-0343840-A2 Particulate polymers, their production and uses Ciba Specialty Chemicals Water Treatments Limited (GB) 1989-11-29 EP disclosed