Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22196466 | 1.00 | CTSK (0.44) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7831409 | 1.00 | CTSK (0.44) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL691120 | 0.89 | CTSK (0.46) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL12487322 | 0.83 | CA1 (0.39) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL7804172 | 0.81 | KDM4E (0.38) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL2341219 | 0.79 | CA1 (0.46) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL10650736 | 0.79 | CTSK (0.46) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL5146358 | 0.79 | CTSS (0.45) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL9527678 | 0.78 | ATM (0.55) | CTSKCTSSCA1CA7CA12 | |
| SCHEMBL10377816 | 0.78 | ATM (0.55) | CTSKCTSSCA1CA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202964-A1 | CONDENSED INDOLINE DERIVATIVES AND THEIR USE AS 5HT, IN PARTICULAR 5HT2C, RECEPTOR LIGANDS | VERNALIS RESEARCH LIMITED (GB) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001012602-A1 | CONDENSED INDOLINE DERIVATIVES AND THEIR USE AS 5HT, IN PARTICULAR 5HT2C, RECEPTOR LIGANDS | VERNALIS RESEARCH LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |