Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554544 | 0.90 | ACHE (0.49) | ACHECCR2DRD3HTTALDH1A1 | |
| SCHEMBL7546108 | 0.87 | CCR2 (0.49) | ACHECCR2DRD3HTTALDH1A1 | |
| SCHEMBL7547919 | 0.87 | AURKA (0.51) | ACHECCR2ALDH1A1KDM4ERAB9A | |
| SCHEMBL7549579 | 0.87 | NPC1 (0.53) | ACHEATP4AATP4BALDH1A1KDM4E | |
| SCHEMBL7551037 | 0.87 | ACHE (0.59) | ACHECCR2ALDH1A1KDM4ERAB9A | |
| SCHEMBL7550694 | 0.87 | CCR2 (0.58) | ACHECCR2DRD3DRD2ALDH1A1 | |
| SCHEMBL7569900 | 0.85 | CCR2 (0.72) | ACHECCR2ALDH1A1KDM4EGFER | |
| SCHEMBL7160843 | 0.85 | AURKA (0.51) | ACHECCR2 | |
| SCHEMBL7550508 | 0.85 | CCR2 (0.45) | ACHECCR2DRD3DRD2HTT | |
| SCHEMBL7550047 | 0.84 | ACHE (0.46) | ACHECCR2HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | CCR1, CCR2, CCR8 | ACHE 4652/4885CCR2 2/4885DRD3 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.