Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 8/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549617 | 0.92 | CYP11B1 (0.48) | RPS6KA5CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7155399 | 0.88 | NPC1 (0.60) | RPS6KA5CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7548733 | 0.87 | MAPT (0.54) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL7555014 | 0.87 | KDM4E (0.60) | RPS6KA5CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7159278 | 0.85 | NPC1 (0.43) | RPS6KA5CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7551302 | 0.82 | CYP1A2 (0.39) | CYP11B1CYP11B2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7153692 | 0.82 | NPC1 (0.48) | CYP11B1CYP11B2KDM4EALDH1A1HPGD | |
| SCHEMBL8518781 | 0.81 | NPC1 (0.52) | RPS6KA5CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7546958 | 0.81 | CYP11B1 (0.38) | CYP11B1CYP11B2KDM4EALDH1A1HPGD | |
| SCHEMBL7551005 | 0.80 | MYC (0.42) | CYP11B1CYP11B2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | CCR1, CCR2, CCR8 | RPS6KA5 3324/4885CYP11B1 842/4885CYP11B2 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.