Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553956 | 0.87 | MYC (0.47) | MYCNPY5RNLRP3KDM4EMEN1 | |
| SCHEMBL7546958 | 0.86 | CYP11B1 (0.38) | NPY5RCYP11B1CYP11B2NLRP3HDAC1 | |
| SCHEMBL7160215 | 0.86 | MYC (0.35) | MYCHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL7551302 | 0.83 | CYP1A2 (0.39) | CYP11B1CYP11B2HDAC1HDAC8HDAC6 | |
| SCHEMBL7549617 | 0.82 | CYP11B1 (0.48) | CYP11B1CYP11B2NLRP3HDAC1HDAC8 | |
| SCHEMBL7550136 | 0.80 | RPS6KA5 (0.46) | CYP11B1CYP11B2NLRP3HDAC1HDAC8 | |
| SCHEMBL7548733 | 0.79 | MAPT (0.54) | NLRP3HDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL7159220 | 0.76 | CYP1A2 (0.44) | HDAC1HDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL7153735 | 0.75 | NPY5R (0.49) | NPY5RCYP3A4ADORA2AADORA1 | |
| SCHEMBL7156596 | 0.75 | BACE1 (0.38) | CYP11B1CYP11B2HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | CCR1, CCR2, CCR8 | MYC 1559/4885NPY5R 649/4885CYP11B1 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.