SCHEMBL7550172

SCHEMBL7550172

Cc1cn(CC(=O)N(C[C]=O)CCCC=O)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.39
KMT2A Q03164 1/20 0.37
MAPK1 P28482 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6837658 0.85 MAPK1 (0.40) TK1KMT2AMAPK1HPGD
SCHEMBL3918733 0.84 KMT2A (0.39) TK1KMT2AMAPK1HPGD
SCHEMBL3924762 0.79 TK1 (0.39) TK1MAPK1HPGD
SCHEMBL3920039 0.78 TK1 (0.39) TK1MAPK1HPGD
SCHEMBL3930081 0.77 TK1 (0.40) TK1MAPK1
SCHEMBL3918640 0.76 TK1 (0.41) TK1MAPK1HPGD
SCHEMBL3918737 0.75 TK1 (0.40) TK1MAPK1HPGD
SCHEMBL3926875 0.75 TK1 (0.40) TK1MAPK1HPGD
SCHEMBL6837655 0.75 TYMP (0.43) TK1KMT2AMAPK1HPGD
SCHEMBL6837969 0.73 TYMP (0.41) TK1KMT2AMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672677-B1 Polyamide-oligonucleotide derivatives, their production and use AVENTIS PHARMA GMBH (DE) 2002-07-03 EP disclosed