Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944333 | 0.83 | GSK3B (0.50) | GSK3BPTPN1CA12CA1CA2 | |
| SCHEMBL7410393 | 0.83 | CA1 (0.58) | GSK3BPTPN1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7550418 | 0.83 | GSK3B (0.50) | GSK3BPTPN1CA12CA1CA2 | |
| SCHEMBL11344524 | 0.80 | NR4A2 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6888383 | 0.80 | LMNA (0.54) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL9409741 | 0.79 | GSK3B (0.70) | GSK3BPTPN1TDP1MEN1KMT2A | |
| SCHEMBL23553765 | 0.79 | MEN1 (0.62) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL7108177 | 0.79 | TDP1 (0.54) | GSK3BPTPN1ALDH1A1TDP1MEN1 | |
| SCHEMBL30041713 | 0.79 | MEN1 (0.62) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL7912398 | 0.79 | HSD11B1 (0.46) | CA12CA1CA2CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051410-A2 | PHENYLTHIAZOLE AND THIAZOLINE DERIVATIVES AND THEIR USE AS ANTIPARASITICS | AKZO NOBEL N.V. (NL) | 2002-07-04 | — | — | WO | disclosed |