Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192982 | 0.79 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL7550415 | 0.70 | TSHR (0.35) | LMNACYP3A4TSHR | |
| SCHEMBL15927760 | 0.69 | ALDH1A1 (0.34) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL7551220 | 0.68 | — | — | |
| SCHEMBL4524185 | 0.65 | LMNA (0.46) | LMNACYP3A4TSHR | |
| SCHEMBL5323083 | 0.64 | SLC6A2 (0.44) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL12020283 | 0.63 | SLC6A2 (0.44) | CHRM1SLC6A2SLC6A3KDM4ELMNA | |
| SCHEMBL9133419 | 0.63 | CHRM2 (0.33) | CHRM2CHRM4CHRM1CHRM3CHRNB2 | |
| SCHEMBL18979128 | 0.63 | ACHE (0.36) | SIGMAR1ALDH1A1LMNA | |
| SCHEMBL7548459 | 0.62 | TSHR (0.37) | SLC6A2SLC6A3LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150298111-A1 | Ruthenium Or Osmium Complex, Method For Its Preparation And Use Thereof | Instytut Chemii Organicznej Polskiej Akademii Nauk (PL) | 2015-10-22 | — | — | US | disclosed |
| WO-2013045876-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150298111-A1 | Ruthenium Or Osmium Complex, Method For Its Preparation And Use Thereof | OSTC, MRPL21, AP1M1 | CHRM2 1323/4885CHRM4 1744/4885CHRM1 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.