Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 7/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554214 | 0.86 | CTSB (0.57) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6183202 | 0.83 | CTSL (0.64) | TDP1CTSBGFERKMT2ACTSL | |
| SCHEMBL7554406 | 0.83 | CTSB (0.61) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7490182 | 0.82 | CTSB (0.52) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6182114 | 0.79 | CTSB (0.58) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6182791 | 0.78 | CTSB (0.61) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6183809 | 0.78 | CTSB (0.61) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6183805 | 0.78 | CTSB (0.61) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6182874 | 0.78 | CTSB (0.61) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7452244 | 0.78 | CTSB (0.61) | CTSBKMT2ACTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |