Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7551529

N.Nc1ccc(N)c(S(=O)(=O)O)c1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
RECQL P46063 4/20 0.53
HSD17B10 Q99714 4/20 0.53
TSHR P16473 3/20 0.53
CASP1 P29466 2/20 0.53
THRB P10828 2/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
RAPGEF4 Q8WZA2 1/20 0.53
TDP1 Q9NUW8 5/20 0.50
POLB P06746 3/20 0.50
MAPT P10636 3/20 0.50
CASP6 P55212 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50
APEX1 P27695 2/20 0.50
NSD2 O96028 2/20 0.50
APOBEC3A P31941 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7551537 1.00 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
SCHEMBL115254 0.98 ALDH1A1 (0.55) ALDH1A1RECQLHSD17B10TSHRCASP1
SCHEMBL29349546 0.98 ALDH1A1 (0.55) ALDH1A1RECQLHSD17B10TSHRCASP1
Lithium SCHEMBL30894454 0.96 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
SCHEMBL10487045 0.96 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
SCHEMBL10487054 0.96 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
Lithium SCHEMBL30894455 0.96 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
SCHEMBL29226024 0.96 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
Hydrochloric Acid SCHEMBL18894304 0.96 ALDH1A1 (0.53) ALDH1A1RECQLHSD17B10TSHRCASP1
SCHEMBL6260904 0.90 RAPGEF4 (0.49) ALDH1A1RECQLHSD17B10TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747418-B1 Aromatic polyimide and gas separation UBE INDUSTRIES (JP) 2002-07-03 EP disclosed
US-5744575-A Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1998-04-28 US disclosed
EP-0747418-A1 Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1996-12-11 EP disclosed