Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029405 | 0.84 | EPAS1 (0.36) | ADORA2AADORA1EPAS1DRD2 | |
| SCHEMBL5896833 | 0.80 | CYP3A4 (0.38) | — | |
| SCHEMBL7580596 | 0.79 | EPAS1 (0.37) | ADORA2AADORA1EPAS1DRD2 | |
| SCHEMBL19009972 | 0.77 | HSD11B1 (0.30) | — | |
| SCHEMBL7033701 | 0.76 | KMT2A (0.36) | ADORA2AADORA1EPAS1DRD2 | |
| SCHEMBL7030626 | 0.72 | GAA (0.39) | — | |
| SCHEMBL7030271 | 0.71 | DRD2 (0.32) | EPAS1DRD2 | |
| SCHEMBL8647653 | 0.70 | DRD2 (0.34) | ADORA2AADORA1EPAS1DRD2 | |
| SCHEMBL5897025 | 0.68 | MAPT (0.32) | — | |
| SCHEMBL13338228 | 0.67 | CYP3A4 (0.33) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826691-B1 | Optically active diphosphine compound, method for making the compound, transition metal complex having the compound as ligand and method for making optically active substance by use of the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-5847222-A | Optically active diphosphine compound, method for making the compound, transition metal complex having the compound as ligand and method for making optically active substance by use of the complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0826691-A2 | Optically active diphosphine compound, method for making the compound, transition metal complex having the compound as ligand and method for making optically active substance by use of the complex | Takasago International Corporation (JP) | 1998-03-04 | — | — | EP | disclosed |