Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 9/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515470 | 0.96 | ALDH1A1 (0.33) | ALDH1A1HTTMAPTDPP4ACACB | |
| SCHEMBL7559233 | 0.85 | TSHR (0.40) | ALDH1A1HTTMAPTROCK2GPR119 | |
| SCHEMBL7511353 | 0.84 | AAK1 (0.36) | ALDH1A1HTTROCK2 | |
| SCHEMBL4517066 | 0.83 | PDE6D (0.34) | ALDH1A1HTTACACB | |
| SCHEMBL7513215 | 0.81 | ACACB (0.40) | ACACB | |
| SCHEMBL7513387 | 0.81 | PIM1 (0.39) | — | |
| SCHEMBL4526756 | 0.80 | F10 (0.34) | ALDH1A1HTTMAPTDPP4ACACB | |
| SCHEMBL7512228 | 0.80 | KDM4D (0.33) | ALDH1A1HTTROCK2 | |
| SCHEMBL4501896 | 0.79 | ROCK2 (0.44) | ALDH1A1HTTMAPTDPP4ROCK2 | |
| SCHEMBL4515472 | 0.78 | IRAK1 (0.38) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |