Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809605 | 0.82 | MME (0.51) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL6130478 | 0.82 | MME (0.51) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL6130477 | 0.82 | MME (0.51) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL9809609 | 0.82 | MME (0.51) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL7211707 | 0.82 | MME (0.51) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL5842234 | 0.82 | FPR2 (0.47) | MMENPSR1ALPIPKMPTGS1 | |
| SCHEMBL27935562 | 0.81 | ITGB3 (0.50) | MMENPSR1SRRALPIPKM | |
| SCHEMBL5017008 | 0.81 | FPR2 (0.51) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL8758356 | 0.81 | MME (0.50) | MMENPSR1FPR2NAALAD2MMP2 | |
| SCHEMBL2954527 | 0.81 | MME (0.50) | MMENPSR1SRRALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001972-A1 | SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006431-A1 | SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |