SCHEMBL755300

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16921581	0.82	PDE3B (0.42)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL765461	0.77	MAPT (0.51)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL754651	0.77	LIPG (0.45)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL823438	0.73	ALDH1A1 (0.46)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL4677310	0.72	HDAC4 (0.54)	KDM4EMAPTALDH1A1LMNAHPGD
	SCHEMBL4716961	0.72	PDE3B (0.46)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL18796715	0.71	PDE3B (0.78)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL23453758	0.69	PDE3B (0.51)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL759556	0.69	ALDH1A1 (0.48)	PDE3BPDE3AKDM4EMAPTALDH1A1
	SCHEMBL1828976	0.69	HDAC4 (0.65)	KDM4EMAPTALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.