Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.68 |
| ▸ | MMP3 | P08254 | 9/20 | 0.68 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450397 | 0.86 | MMP1 (0.73) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7404453 | 0.86 | MMP1 (0.73) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7404455 | 0.86 | MMP1 (0.73) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7366454 | 0.80 | MMP1 (0.52) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7406308 | 0.80 | MMP1 (0.52) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7366457 | 0.80 | MMP1 (0.52) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7366452 | 0.80 | MMP1 (0.52) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7367853 | 0.73 | MMP1 (0.71) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7362322 | 0.72 | MMP1 (0.71) | MMP1MMP3MMP9MMP7MMP8 | |
| SCHEMBL7362319 | 0.72 | MMP1 (0.71) | MMP1MMP3MMP9MMP7MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008853-A9 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | — | 1998-08-06 | — | — | WO | disclosed |