Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.65 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895460 | 0.93 | TLR7 (0.73) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL6719054 | 0.84 | TLR7 (0.50) | TLR7NUDT1LMNAPOLBHRH2 | |
| Propionic Acid SCHEMBL6724139 | 0.83 | NPC1 (0.46) | TLR7NUDT1LMNAPOLBHRH2 | |
| Propionic Acid SCHEMBL6719538 | 0.83 | TLR7 (0.62) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL10732746 | 0.79 | TLR7 (0.51) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL29508382 | 0.79 | TLR7 (1.00) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL189202 | 0.79 | TLR7 (1.00) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL10587717 | 0.75 | NPC1 (0.48) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL9602030 | 0.74 | TLR7 (0.47) | TLR7NUDT1LMNAPOLBHRH2 | |
| Acetic Acid SCHEMBL8326365 | 0.74 | TLR7 (0.46) | TLR7NUDT1LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872478-B1 | Intermediates for the preparation of 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines | MINNESOTA MINING & MFG (US) | 2002-12-18 | — | — | EP | disclosed |