Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 16/20 | 0.40 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691265 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1ALDH1A1AKR1B1ADAMTS5 | |
| SCHEMBL11676230 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1ALDH1A1AKR1B1ADAMTS5 | |
| SCHEMBL7553174 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1ALDH1A1AKR1B1MMP2 | |
| SCHEMBL21404017 | 0.79 | ADAMTS5 (0.46) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL11146108 | 0.78 | MMP2 (0.46) | SMN1; SMN2NPSR1ALDH1A1AKR1B1MMP2 | |
| SCHEMBL11484364 | 0.78 | MMP2 (0.46) | SMN1; SMN2NPSR1ALDH1A1AKR1B1MMP2 | |
| SCHEMBL1404434 | 0.78 | MMP2 (0.46) | SMN1; SMN2NPSR1ALDH1A1AKR1B1MMP2 | |
| SCHEMBL8893756 | 0.78 | MMP2 (0.46) | SMN1; SMN2NPSR1ALDH1A1AKR1B1MMP2 | |
| SCHEMBL1404438 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2NPSR1ALDH1A1AKR1B1ADAMTS5 | |
| SCHEMBL22129834 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1ALDH1A1AKR1B1ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571904-B1 | Process for preparing methylolhydantoins | LONZA AG (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0571904-A1 | Process for preparing methylolhydantoins | LONZA INC. (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5252744-A | Liquid based methods for the production of solid, anhydrous methylolhydantoins | LONZA INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-4061542-A | 2-Methyl-L-arginine produced by cultivating streptomyces strain | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |