SCHEMBL7553189

SCHEMBL7553189

C=CCOc1ccc2cc(-c3ccc(CCCCCC(C)F)cc3)ncc2c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.42
NPC1 O15118 6/20 0.42
CASP3 P42574 3/20 0.42
SENP7 Q9BQF6 3/20 0.42
SRC P12931 2/20 0.37
ABL1 P00519 1/20 0.37
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
CA12 O43570 4/20 0.34
CA1 P00915 4/20 0.34
CA9 Q16790 4/20 0.34
CASR P41180 1/20 0.34
BMP1 P13497 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7556194 0.94 RAB9A (0.39) RAB9ANPC1CASP3SENP7SRC
SCHEMBL8601714 0.88 RAB9A (0.42) RAB9ANPC1CASP3SENP7SRC
SCHEMBL7556410 0.87 SRC (0.40) SRCABL1MAPTCA12CA1
SCHEMBL7555471 0.87 MAPT (0.42) RAB9ANPC1CASP3SENP7MAPT
SCHEMBL7555281 0.87 MAPT (0.42) RAB9ANPC1CASP3SENP7SRC
SCHEMBL7558650 0.87 RAB9A (0.36) RAB9ANPC1CASP3SENP7MAPT
SCHEMBL7560108 0.86 RAB9A (0.44) RAB9ANPC1CASP3SENP7MAPT
SCHEMBL7560826 0.85 RAB9A (0.43) RAB9ANPC1CASP3SENP7MAPT
SCHEMBL8599483 0.85 CA12 (0.40) SRCABL1MAPTCA12CA1
SCHEMBL7552397 0.85 RAB9A (0.36) RAB9ANPC1CASP3SENP7MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708165-B1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2002-01-09 EP disclosed
US-6246452-B1 FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed