SCHEMBL7555281

SCHEMBL7555281

C=CCOc1ccc2nc(-c3ccc(CCCCCC(C)F)cc3)ccc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.42
MAOB P27338 2/20 0.39
SRC P12931 2/20 0.36
ABL1 P00519 1/20 0.36
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
CASR P41180 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7551168 0.94 MAPT (0.38) MAPTMAOBSRCABL1RAB9A
SCHEMBL7553189 0.87 RAB9A (0.42) MAPTSRCABL1RAB9ASMN1; SMN2
SCHEMBL7556410 0.87 SRC (0.40) MAPTSRCABL1SMN1; SMN2CA12
SCHEMBL8601714 0.85 RAB9A (0.42) MAPTSRCABL1RAB9ASMN1; SMN2
SCHEMBL7552164 0.85 ESR1 (0.34) MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL7554341 0.84 MAPT (0.39) MAPTRAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL8599483 0.84 CA12 (0.40) MAPTSRCABL1SMN1; SMN2CA12
SCHEMBL7556378 0.83 MAPT (0.41) MAPTMAOBSRCABL1RAB9A
SCHEMBL7556381 0.83 MAPT (0.41) MAPTMAOBSRCABL1RAB9A
SCHEMBL7560108 0.83 RAB9A (0.44) MAPTRAB9ASMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708165-B1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2002-01-09 EP disclosed
US-6246452-B1 FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0708165-A1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-24 EP disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed