SCHEMBL7553199

SCHEMBL7553199

c1coc(CN2CN(Cc3ccco3)CN(Cc3ccco3)C2)c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
HTT P42858 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.51
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.47
POLB P06746 1/20 0.47
ATM Q13315 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
TRPV6 Q9H1D0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11265977 0.90 ALDH1A1 (0.49) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL11271539 0.87 ALDH1A1 (0.47) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL8045561 0.83 SIGMAR1 (0.55) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL31670698 0.83 SIGMAR1 (0.55) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL9551657 0.81 SIGMAR1 (0.54) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL14662295 0.79 CYP2D6 (0.51) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL8722265 0.79 ALDH1A1 (0.54) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL17157069 0.79 SMN1; SMN2 (0.55) ALDH1A1HTTCYP2D6CYP2C9CYP2C19
SCHEMBL4906722 0.78 SIGMAR1 (0.52) ALDH1A1GAAMAPTHTTNPSR1
SCHEMBL12536025 0.78 CYP2D6 (0.54) ALDH1A1MAPTHTTCYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004610-A2 Composition for inhibiting the growth of microorganisms in metal working fluid and method for inhibiting the growth of microorganisms in such fluids MERCK & CO. INC. (US) 1979-10-17 EP claimed
US-4149983-A 1,3,5-TRIS-(FURFURYL) HEXAHYDROTRIAZINE MERCK & CO., INC. (US) 1979-04-17 US claimed
EP-3820948-B1 AN ANTI-FOULING DISPERSANT COMPOSITION AND METHOD OF USE BL TECHNOLOGIES INC (US) 2023-10-11 EP disclosed
WO-2001042405-A9 WATER SOLUBLE VEGETABLE OIL ESTERS FOR INDUSTRIAL APPLICATIONS CARGILL INC (US) 2002-08-15 WO disclosed
US-6271185-B1 TRANSESTERIFICATION VEGETABLE OIL WITH TRIETHANOLAMINE CARGILL, INCORPORATED 2001-08-07 US disclosed
WO-2001042405-A2 WATER SOLUBLE VEGETABLE OIL ESTERS FOR INDUSTRIAL APPLICATIONS CARGILL INCORPORATED (US) 2001-06-14 WO disclosed
US-5716917-A AQUEOUS MIXTURE CONTAINING NATURAL ORGANIC LUBRICANT, SURFACTANTS AND WATER SOLUBLE CATIONIC MICROBIOCIDE CINCINNATI MILACRON INC. (US) 1998-02-10 US disclosed
EP-0001738-B1 1,3,5-S-HEXAHYDROTRISUBSTITUTED TRIAZINES AND METAL-WORKING COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1982-01-06 EP disclosed
EP-0004610-A3 COMPOSITION FOR INHIBITING THE GROWTH OF MICROORGANISMS IN METAL WORKING FLUID AND METHOD FOR INHIBITING THE GROWTH OF MICROORGANISMS IN SUCH FLUIDS MERCK & CO. INC. (US) 1979-10-31 EP disclosed
EP-0004610-A2 Composition for inhibiting the growth of microorganisms in metal working fluid and method for inhibiting the growth of microorganisms in such fluids MERCK & CO. INC. (US) 1979-10-17 EP disclosed
EP-0004610-A2 Composition for inhibiting the growth of microorganisms in metal working fluid and method for inhibiting the growth of microorganisms in such fluids MERCK & CO. INC. (US) 1979-10-17 EP disclosed
US-4159253-A MICROBIOCIDES MERCK & CO., INC. (US) 1979-06-26 US disclosed
US-4159253-A MICROBIOCIDES MERCK & CO., INC. (US) 1979-06-26 US disclosed
EP-0001738-A1 1,3,5-s-Hexahydrotrisubstituted triazines and metal-working compositions containing them MERCK & CO. INC. (US) 1979-05-16 EP disclosed
US-4149983-A 1,3,5-TRIS-(FURFURYL) HEXAHYDROTRIAZINE MERCK & CO., INC. (US) 1979-04-17 US disclosed
US-4149983-A 1,3,5-TRIS-(FURFURYL) HEXAHYDROTRIAZINE MERCK & CO., INC. (US) 1979-04-17 US disclosed
US-4125719-A MICROBIOCIDES MERCK & CO., INC. (US) 1978-11-14 US disclosed
US-4125719-A MICROBIOCIDES MERCK & CO., INC. (US) 1978-11-14 US disclosed