Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559417 | 0.86 | P2RX7 (0.82) | P2RX7 | |
| Hydrochloric Acid SCHEMBL7659490 | 0.86 | P2RX7 (0.80) | P2RX7 | |
| SCHEMBL7663299 | 0.81 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL5336494 | 0.79 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL7665305 | 0.79 | P2RX7 (0.83) | P2RX7AVPR1A | |
| SCHEMBL7657585 | 0.78 | P2RX7 (0.93) | P2RX7AVPR1A | |
| SCHEMBL4129123 | 0.77 | P2RX7 (0.86) | P2RX7 | |
| SCHEMBL7669003 | 0.77 | AVPR1A (0.74) | P2RX7AVPR1A | |
| SCHEMBL7660351 | 0.77 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL7656374 | 0.77 | P2RX7 (1.00) | P2RX7AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | claimed |
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |
| EP-1171432-A1 | ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061569-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |