Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | PKM | P14618 | 3/20 | 0.77 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758235 | 0.91 | SIRT6 (0.64) | KMT2APKMSIRT6MEN1SIRT3 | |
| SCHEMBL13805528 | 0.89 | SIRT6 (0.65) | KMT2APKMSIRT6MEN1SIRT3 | |
| SCHEMBL6346820 | 0.89 | KMT2A (0.65) | KMT2APKMSIRT6MEN1MAPT | |
| SCHEMBL10763914 | 0.87 | KMT2A (0.69) | KMT2APKMMEN1MAPTKDM4E | |
| Benzoylpas SCHEMBL563122 | 0.87 | KMT2A (1.00) | KMT2APKMSIRT6MEN1MAPT | |
| SCHEMBL11593167 | 0.86 | KMT2A (0.76) | KMT2APKMMEN1MAPTKDM4E | |
| SCHEMBL7553405 | 0.86 | KMT2A (0.61) | KMT2APKMSIRT6MEN1SIRT3 | |
| SCHEMBL10759208 | 0.86 | MITF (0.64) | KMT2APKMSIRT6MEN1SIRT3 | |
| SCHEMBL23796858 | 0.85 | SIRT6 (0.58) | KMT2APKMSIRT6MEN1SIRT3 | |
| SCHEMBL30418835 | 0.85 | SIRT6 (0.58) | KMT2APKMSIRT6MEN1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236329-A1 | AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | ITAL-FARMACO S.p.A. (IT) | 1987-09-16 | — | — | EP | claimed |
| WO-1986003199-A1 | AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | ITALFARMACO S.P.A. (IT) | 1986-06-05 | — | — | WO | claimed |
| US-9364424-B2 | Topical cosmetic skin lightening compositions and methods of use thereof | STIEFEL LABORATORIES, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160074315-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. | 2016-03-17 | — | — | US | disclosed |
| US-8283287-B2 | Thermosensitive recording material | RICOH COMPANY, LTD. (JP) | 2012-10-09 | — | — | US | disclosed |
| EP-2036737-B1 | Thermosensitive recording material | RICOH CO LTD (JP) | 2011-02-16 | — | — | EP | disclosed |
| EP-2219600-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009067095-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| US-20090075817-A1 | THERMOSENSITIVE RECORDING MATERIAL | RICOH COMPANY, LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-2036737-A1 | Thermosensitive recording material | Ricoh Company, Ltd. (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | KMT2A 998/4885PKM 3215/4885SIRT6 3550/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | KMT2A 847/4885PKM 531/4885SIRT6 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.