Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555883 | 1.00 | ALOX15 (0.36) | ALOX15MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7553510 | 1.00 | ALOX15 (0.36) | ALOX15MEN1KMT2AALDH1A1POLB | |
| SCHEMBL9604263 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1POLBALOX5 | |
| SCHEMBL10334535 | 0.80 | ALOX15 (0.42) | ALOX15ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL11664024 | 0.73 | ALOX15 (0.33) | ALOX15LMNA | |
| SCHEMBL8308888 | 0.71 | ALOX15 (0.43) | ALOX15ALDH1A1HTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10545348 | 0.69 | ALOX15 (0.40) | ALOX15MEN1KMT2AALOX5SMN1; SMN2 | |
| SCHEMBL1463776 | 0.69 | — | — | |
| SCHEMBL1986826 | 0.68 | ALOX15 (0.44) | ALOX15ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL11495165 | 0.68 | ALOX15 (0.41) | ALOX15ALDH1A1HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833937-B1 | OPTICAL RESOLUTION OF ALKYL 1,4-BENZODIOXAN-2-CARBOXYLATES USING ESTERASE FROM SERRATIA MARCESCENS | SEPRACOR INC (US) | 2002-01-23 | — | — | EP | claimed |