Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420613 | 0.81 | PPARA (0.44) | MEN1KMT2APPARGPPARATSHR | |
| SCHEMBL444321 | 0.81 | CYP2D6 (0.36) | MEN1KMT2APOLBTRPM8PPARG | |
| SCHEMBL3380544 | 0.81 | PPARA (0.44) | MEN1KMT2APPARGPPARATSHR | |
| SCHEMBL7553505 | 0.81 | ALOX15 (0.36) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL7553510 | 0.81 | ALOX15 (0.36) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL7555883 | 0.81 | ALOX15 (0.36) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL7626521 | 0.74 | P2RX1 (0.38) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7634978 | 0.74 | CYP2C19 (0.39) | ALDH1A1CYP2C19CYP1A2NFKB1SMN1; SMN2 | |
| SCHEMBL1463776 | 0.73 | — | — | |
| SCHEMBL20955895 | 0.72 | HTR2A (0.33) | MEN1KMT2AALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266711-A | Process for the preparation of 3-benzoyl benzofuran derivatives | SANOFI (FR) | 1993-11-30 | — | — | US | disclosed |