Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7554182

N.Nc1ccc(S(=O)(=O)O)c(N)c1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.49
ALDH1A1 P00352 8/20 0.48
HSD17B10 Q99714 6/20 0.48
TSHR P16473 3/20 0.48
RECQL P46063 3/20 0.48
CASP1 P29466 3/20 0.48
CYP3A4 P08684 1/20 0.48
THRB P10828 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
NT5E P21589 3/20 0.46
TDP1 Q9NUW8 4/20 0.46
CASP6 P55212 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 2/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
NSD2 O96028 2/20 0.46
APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10336554 1.00 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
Ammonia Solution, Strong SCHEMBL7554180 1.00 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
SCHEMBL343300 0.98 ALDH1A1 (0.50) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
SCHEMBL28723530 0.96 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
SCHEMBL3396551 0.96 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
SCHEMBL6028415 0.96 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
SCHEMBL11426855 0.96 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
Sulfuric Acid SCHEMBL8646813 0.96 ALDH1A1 (0.53) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
SCHEMBL29386364 0.96 ALDH1A1 (0.52) RAPGEF4ALDH1A1HSD17B10TSHRRECQL
Hydrochloric Acid SCHEMBL8641895 0.96 RAPGEF4 (0.49) RAPGEF4ALDH1A1HSD17B10TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102516137-A Production method of 2, JIANGSU YUANZHENG CHEMICAL CO LTD 2012-06-27 CN disclosed
EP-0747418-B1 Aromatic polyimide and gas separation UBE INDUSTRIES (JP) 2002-07-03 EP disclosed
US-5744575-A Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1998-04-28 US disclosed
EP-0747418-A1 Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1996-12-11 EP disclosed