Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6048558 | 0.83 | BACE1 (0.48) | SLC6A4SLC6A2SLC6A3HSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL6048530 | 0.81 | BACE1 (0.47) | SLC6A4SLC6A2SLC6A3HSD17B1HSD17B2 | |
| SCHEMBL6048536 | 0.76 | TAAR1 (0.57) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL28872831 | 0.75 | TSHR (0.54) | TSHRHSD17B1HSD17B2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6048525 | 0.75 | TAAR1 (0.55) | TAAR1SLC6A4SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL3210774 | 0.75 | ALOX15 (0.63) | SLC6A4TSHRSLC6A2SLC6A3CYP3A4 | |
| SCHEMBL12505390 | 0.72 | ALDH1A1 (0.52) | TSHRHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL16574041 | 0.72 | TSHR (0.50) | TSHRHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL28293144 | 0.72 | TSHR (0.54) | TSHRHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL6048555 | 0.71 | SRC (0.52) | TAAR1SLC6A4HSD17B1HSD17B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198251-A1 | Substituted 2-dialkylaminoalkylbiphenyl derivatives | GRUENENTHAL GMBH (DE) | 2002-12-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198251-A1 | Substituted 2-dialkylaminoalkylbiphenyl derivatives | LIPA, PKD1, PKD2 | TAAR1 3902/4885SLC6A4 1586/4885TSHR 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.