Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ELANE | P08246 | 1/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.63 |
| ▸ | GABRD | O14764 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554410 | 0.95 | PPARG (0.81) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL7552521 | 0.93 | PPARG (0.78) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL30213777 | 0.92 | PPARG (0.90) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| Xanthomicrol SCHEMBL6257160 | 0.92 | PPARG (1.00) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL2622796 | 0.92 | PPARG (0.85) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL30051182 | 0.92 | PPARG (0.85) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL30683238 | 0.89 | PPARG (0.85) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL2180082 | 0.89 | PPARG (0.85) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| Isothymusin SCHEMBL31483965 | 0.88 | PPARG (0.87) | PPARGALDH1A1MAPK1MAPTKDM4E | |
| Isothymusin SCHEMBL694063 | 0.88 | PPARG (0.87) | PPARGALDH1A1MAPK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053152-A1 | COMPOSITION CONTAINING FLAVONOIDS FOR TREATMENT BRAIN DISORDERS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE (GB) | 2002-07-11 | — | — | WO | disclosed |
| US-4532254-A | Inhibitor of aldose reductase | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |