Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ELANE | P08246 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051182 | 1.00 | PPARG (0.85) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| Xanthomicrol SCHEMBL6257160 | 0.92 | PPARG (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7554472 | 0.92 | PPARG (0.85) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7554410 | 0.92 | PPARG (0.81) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7552521 | 0.90 | PPARG (0.78) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL30213777 | 0.89 | PPARG (0.90) | PPARGALDH1A1CYP3A4KMT2APKM | |
| Tangeretin SCHEMBL23629519 | 0.87 | ALDH1A1 (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| Tangeretin SCHEMBL29549538 | 0.87 | ALDH1A1 (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| Tangeretin SCHEMBL19740 | 0.87 | ALDH1A1 (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL30445844 | 0.86 | BCL2 (0.79) | PPARGALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | claimed |
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | claimed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-109374762-B | Method for identifying citrus reticulata blanco and citrus reticulata blanco varieties based on metabonomics | 广州中医药大学第一附属医院 | 2021-10-08 | — | — | CN | claimed |
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240167066-A1 | METHOD FOR PRODUCING DEMETHYLATED COMPOUND | DAICEL CORPORATION (JP) | 2024-05-23 | — | — | US | disclosed |
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | disclosed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | disclosed |
| CN-109374762-B | Method for identifying citrus reticulata blanco and citrus reticulata blanco varieties based on metabonomics | 广州中医药大学第一附属医院 | 2021-10-08 | — | — | CN | disclosed |
| CN-112830917-A | Hydroxylated polymethoxyflavone and preparation method thereof | 五邑大学 | 2021-05-25 | — | — | CN | disclosed |
| US-8940789-B2 | Neurite elongation agent, memory-improving agent and anti-Alzheimer agent comprising 4′-demethylnobiletin or 4′-demethyltangeretin as active ingredient, and process for production of the compound | FUJI SANGYO CO., LTD. (JP) | 2015-01-27 | — | — | US | disclosed |
| US-8940789-B2 | Neurite elongation agent, memory-improving agent and anti-Alzheimer agent comprising 4′-demethylnobiletin or 4′-demethyltangeretin as active ingredient, and process for production of the compound | FUJI SANGYO CO., LTD. (JP) | 2015-01-27 | — | — | US | disclosed |
| US-20120101152-A1 | NEURITE ELONGATION AGENT, MEMORY-IMPROVING AGENT AND ANTI-ALZHEIMER AGENT COMPRISING 4'-DEMETHYLNOBILETIN OR 4'-DEMETHYLTANGERETIN AS ACTIVE INGREDIENT, AND PROCESS FOR PRODUCTION OF THE COMPOUND | FUJI SANGYO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120101152-A1 | NEURITE ELONGATION AGENT, MEMORY-IMPROVING AGENT AND ANTI-ALZHEIMER AGENT COMPRISING 4'-DEMETHYLNOBILETIN OR 4'-DEMETHYLTANGERETIN AS ACTIVE INGREDIENT, AND PROCESS FOR PRODUCTION OF THE COMPOUND | FUJI SANGYO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20050181080-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2005-08-18 | — | — | US | disclosed |
| US-20030165533-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-09-04 | — | — | US | disclosed |
| US-20030152588-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-08-14 | — | — | US | disclosed |
| US-4532254-A | Inhibitor of aldose reductase | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101152-A1 | NEURITE ELONGATION AGENT, MEMORY-IMPROVING AGENT AND ANTI-ALZHEIMER AGENT COMPRISING 4'-DEMETHYLNOBILETIN OR 4'-DEMETHYLTANGERETIN AS ACTIVE INGREDIENT, AND PROCESS FOR PRODUCTION OF THE COMPOUND | BDNF, MAP2, ERG28 | PPARG 3984/4885ALDH1A1 1892/4885CYP3A4 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.