Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ELANE | P08246 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622796 | 1.00 | PPARG (0.85) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| Xanthomicrol SCHEMBL6257160 | 0.92 | PPARG (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7554472 | 0.92 | PPARG (0.85) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7554410 | 0.92 | PPARG (0.81) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7552521 | 0.90 | PPARG (0.78) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL30213777 | 0.89 | PPARG (0.90) | PPARGALDH1A1CYP3A4KMT2APKM | |
| Tangeretin SCHEMBL23629519 | 0.87 | ALDH1A1 (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| Tangeretin SCHEMBL29549538 | 0.87 | ALDH1A1 (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| Tangeretin SCHEMBL19740 | 0.87 | ALDH1A1 (1.00) | PPARGALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL30445844 | 0.86 | BCL2 (0.79) | PPARGALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | claimed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | claimed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | claimed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | disclosed |