SCHEMBL7554477

SCHEMBL7554477

Nc1nc(C2CCC2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.33
HRH4 Q9H3N8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602143 0.92 PDE10A (0.39) PDE10A
SCHEMBL10601684 0.78 PDE10A (0.43) PDE10A
SCHEMBL9489467 0.75 HRH4 (0.44) PDE10AHRH4
SCHEMBL808435 0.73 HRH2 (0.43) PDE10AHRH4
SCHEMBL4838901 0.73 HRH2 (0.43) PDE10AHRH4
SCHEMBL18383786 0.73 HRH2 (0.43) PDE10AHRH4
SCHEMBL11733090 0.72 CASP1 (0.33)
SCHEMBL1617690 0.72 KDM4E (0.32)
SCHEMBL8048198 0.71 HRH4 (0.37) PDE10AHRH4
SCHEMBL7193572 0.70 PDE10A (0.45) PDE10AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222178-A1 ALKYL-AMINO-1,3,5-TRIAZINES AND THEIR USE AS HERBICIDES Aventis CropScience GmbH (DE) 2002-07-17 EP disclosed
WO-2001027093-A1 ALKYL-AMINO-1,3,5-TRIAZINES AND THEIR USE AS HERBICIDES AVENTIS CROPSCIENCE GMBH (DE) 2001-04-19 WO disclosed