Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623032 | 0.79 | MKNK1 (0.47) | PREPCA12CA1CA9MKNK1 | |
| SCHEMBL7556356 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL15105024 | 0.73 | MKNK1 (0.39) | PREPKDM4EMKNK1MKNK2SYK | |
| SCHEMBL16171288 | 0.72 | PREP (0.51) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL23491348 | 0.72 | PREP (0.57) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL7552809 | 0.71 | TDP1 (0.43) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL7558423 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTCLK4 | |
| SCHEMBL6763899 | 0.70 | PREP (0.53) | PREPCA12CA1CA9KDM4E | |
| SCHEMBL30629151 | 0.69 | PREP (0.41) | PREPCA12CA1CA9 | |
| SCHEMBL9958908 | 0.69 | CCR1 (0.42) | PREPCA12CA1CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036081-B1 | HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS | CIBA SC HOLDING AG (CH) | 2002-07-17 | — | — | EP | disclosed |
| US-6417363-B1 | POLYMERIZATION, RING-CLOSURE METATHESIS, OLIGOMERIZATION, AND CYCLIZATION CATALYSTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-07-09 | — | — | US | disclosed |
| EP-1036081-A1 | HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS | Ciba SC Holding AG (CH) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029701-A1 | HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-06-17 | — | — | WO | disclosed |