Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549557 | 0.89 | DPP7 (0.49) | MAP4K4DPP7ACHEPARP1ALDH1A1 | |
| SCHEMBL7549696 | 0.85 | ACHE (0.53) | MAP4K4DPP7ATRACHEPARP1 | |
| SCHEMBL7554554 | 0.85 | MAP4K4 (0.48) | MAP4K4DPP7ATRPARP1 | |
| SCHEMBL7549558 | 0.84 | MAP4K4 (0.48) | MAP4K4DPP7ATRACHEPARP1 | |
| SCHEMBL7554505 | 0.84 | MAP4K4 (0.48) | MAP4K4DPP7ATRACHEPARP1 | |
| SCHEMBL7548837 | 0.81 | CCR2 (0.54) | MAP4K4DPP7ATRHSP90AA1HSP90AB1 | |
| SCHEMBL7547685 | 0.80 | ACHE (0.56) | MAP4K4DPP7ATRHSP90AA1HSP90AB1 | |
| SCHEMBL7553583 | 0.80 | MAP4K4 (0.48) | MAP4K4DPP7ATRHSP90AA1HSP90AB1 | |
| SCHEMBL7550672 | 0.79 | DPP7 (0.42) | DPP7ACHEALDH1A1KDM4EHPGD | |
| SCHEMBL7554497 | 0.77 | CCR2 (0.54) | ACHEHDAC6ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | CCR1, CCR2, CCR8 | MAP4K4 1964/4885DPP7 2503/4885ATR 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.